The genetic causes of infertility in patients with oligozoospermia and azoospermia in Turkish population

Objective: Advances in the science of genetics and development assisted reproductive techniques focus on genetic causes infertility. The aim this research is to reveal abnormalities terms sex chromosome aneuploidy Y microdeletions. Material Methods: A total 350 patients with azoospermia or severe oligozoospermia were selected. After general examination laboratory investigations performed, cartoypes microdeletions examined. Results: 225 infertile men non-obstructive (NOA) 125 enrolled into study. overall cytogenetic anomaly rate was 16%. Chromosomal changes detected 32 (9.1%) cases. most common 47, XXY (Klinefelter syndrome) incidence 11.5% NOA group. This 3.2% 24 (6.8%) similarly, it observed more frequently group than Conclusion: have been increasing severity As a result, screening appropriate counseling are needed before use techniques. Keywords: azospermia, chromosome, infertility, microdeletion, oligozoospermiaage